Simulated data inspired by the FLOW study (Perkovic 2024)...elt() The following variables are considered in this simulated data set

  • time: time of first event in years (first major irreversible kidney event or non-related death)

  • status: event type at first major irreversible kidney event (=1), non-related death (=2), or right censoring (=0)

  • y: clinical outcome measurement (eGFR) at landmark time (:=2)

  • r: missing indicator for y (1 if observed, 0 if either t<2 or if the outcome was not measured for other reasons)

  • a: binary treatment (1 := active, 0 := placebo)

  • x1: covariate, clinical outcome at baseline (eGFR)

  • x2: covariate, binary treatment usage indicator (1: SGLT2 treatment, 0: none).

The actual failure times and censoring times are also included (failure.time, cens.time), and the full-data outcome (y0) given t>2.

Source

Simulated data

References

Perkovic, V., Tuttle, K. R., Rossing, P., Mahaffey, K. W., Mann, J. F., Bakris, G., Baeres, F. M., Idorn, T., Bosch-Traberg, H., Lausvig, N. L., and Pratley, R. (2024). Effects of semaglutide on chronic kidney disease in patients with type 2 diabetes. New England Journal of Medicine, 391(2):109–121.

Examples

data(truncatedscore)